Russian Journal of Biotechnology Articles archive Archive 2014 N 4 The Space Experiment BIOEMULSION: Results and Prospects

The Space Experiment BIOEMULSION: Results and Prospects

Автор: A.I. Kobatov, N.B. Verbitskaya, and O.V. Dobrolezh

Страница: 63-73


The Space Experiment BIOEMUL­SION: Results and Prospects

Russian Journal of Biotechnology, 2014, N 4, P. 63-73

UDC 579.65

Section:  “Biologicals Technology”


A.I. Kobatov *,  N.B. Verbitskaya,  and  O.V. Dobrolezh

The State Research Institute of Highly Pure Biopreparations (IHPB),  197110, St.-Petersburg Russia



The results of a long-duration (2007—2013) space experiment “Bioemulsion” on the study of a Vitaflor preparation, a next-generation immunobiological based on Lactobacillus acidophilus strains D-75 and D-76, are represented. Vitaflor was designed and manufactured at IHPB and was demonstrated to be safe, to possess high therapeutic efficacy and not to cause allergic effects. Vitaflor was beneficial to both qualitative and quantitative characteristics of host mucosal microflora and to host immune and neuroendocrine systems. The preparation was subjected to a long-term culturing at the International Space Station (ISS), in an enclosed fermentor or hybridization equipment of the Recomb set (from RKK Energiya) in order to obtain a fermented dairy probiotic. A basic possibility to produce the desired product for the prophylaxis and therapy of microecological and immune disorders in astronauts during long space expeditions by the efforts of a space crew was demonstrated. The obtained at ISS preparation exhibits the properties typical  of Vitaflor and fully complies with the requirements to functional nutrition products with probiotic and immune modulating effects.


Key words:  ISS,  Lactobacillus acidophilus,  microgravitation,  probiotic «Vitaflor»,  space experiment “Bioemulsion”,  technology for production of probiotic fermented product.


23.03.2015, 1356 просмотров.


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